| Citation | Packer JS, Zhu Q, Huynh C, Sivaramakrishnan P, Preston E, Dueck H, Stefanik D, Tan K, Trapnell C, Kim J, Waterston RH, Murray JI. A lineage-resolved molecular atlas of C. elegans embryogenesis at single-cell resolution. Science, 2019. |
| PubMed ID | 31488706 |
| Short Description | A lineage-resolved molecular atlas of C. elegans embryogenesis at single-cell resolution. GEO Record: GSE126954, Platform: GPL19757 Lab Atlas: https://wormseq.org/ Other resources: N.A. |
| # of Conditions | 1 |
Full Description
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We sequence the transcriptomes of 86,024 single cells from C. elegans embryos, spanning from gastrulation to the beginning of cuticle synthesis. We identify the lineage (from the invariant C. elegans cell lineage) and approximate developmental age of each cell in the single cell data. Using these annotations, we investigate the competing influences of cell lineage and cell fate on gene expression. |
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