| Citation | Cao J, Packer JS, Ramani V, Cusanovich DA, Huynh C, Daza R, Qiu X, Lee C, Furlan SN, Steemers FJ, Adey A, Waterston RH, Trapnell C, Shendure J. Comprehensive single cell transcriptional profiling of a multicellular organism by combinatorial indexing Science, 2017. |
| PubMed ID | 28818938 |
| Short Description | Comprehensive single cell transcriptional profiling of a multicellular organism by combinatorial indexing GEO Record: GSE98561, Platform: GPL19757 Lab Atlas: N.A. Other resources: N.A. |
| # of Conditions | 1 |
Full Description
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We developed a combinatorial indexing strategy to profile the transcriptomes of large numbers of single cells or nuclei (Single cell Combinatorial Indexing RNA-seq or sci-RNA-seq). We applied sci-RNA-seq to profile nearly 50,000 cells from C. elegans at the L2 stage, effectively ~56-fold “shotgun cellular coverage” of its somatic cell composition. |
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