| Citation | Romagnolo B, Jiang M, Kiraly M, Breton C, Begley R, Wang J, Lund J, Kim SK. Downstream targets of let-60 Ras in Caenorhabditis elegans. Dev Biol, 2002. |
| PubMed ID | 12074557 |
| Short Description | Downstream targets of let-60 Ras in Caenorhabditis elegans. GEO Record: GSE2974 Platform: GPL2653 Download gene-centric, log2 transformed data: WBPaper00005376.ce.mr.csv |
| # of Conditions | 29 |
Full Description
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In Caenorhabditis elegans, let-60 Ras controls many cellular processes, such as differentiation of vulval epithelial cells, function of chemosensory neurons, and meiotic progression in the germ line. Although much is known about the let-60 Ras signaling pathway, relatively little is understood about the target genes induced by let-60 Ras signaling that carry out terminal effector functions leading to morphological change. We have used DNA microarrays to identify 708 genes that change expression in response to activated let-60 Ras. Experimental Details: [cgc5376]:let-23(sy1)_32h [cgc5376]:let-23(sy1)_34h [cgc5376]:let-23(sy1)_36h [cgc5376]:let-23(sy1)_38h [cgc5376]:let-23(sy1)_40h [cgc5376]:let-23(sy1)_42h [cgc5376]:let-23(sy1)_44h [cgc5376]:let-60(n1046)_32h [cgc5376]:let-60(n1046)_34h [cgc5376]:let-60(n1046)_36h [cgc5376]:let-60(n1046)_38h [cgc5376]:let-60(n1046)_40h [cgc5376]:let-60(n1046)_42h [cgc5376]:let-60(n1046)_44h [cgc5376]:let-60_heat_shock_T0 [cgc5376]:let-60_heat_shock_T0_5 [cgc5376]:let-60_heat_shock_T1 [cgc5376]:let-60_heat_shock_T2 [cgc5376]:WT_32h [cgc5376]:WT_34h [cgc5376]:WT_36h [cgc5376]:WT_38h [cgc5376]:WT_40h [cgc5376]:WT_42h [cgc5376]:WT_44h [cgc5376]:WT_heat_shock_T0 [cgc5376]:WT_heat_shock_T0_5 [cgc5376]:WT_heat_shock_T1 [cgc5376]:WT_heat_shock_T2. |
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